α-Solanine is a steroidal glycoalkaloid found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It can occur naturally in any part of the plant, including the leaves, fruit, and tubers.
It is very toxic even in small quantities. and it is one of the plant's natural defenses. Solanine was first isolated in 1820 by Desfosses from the berries of the European black nightshade (Solanum nigrum), after which it was named.
Solanine has fungicidal and pesticidal properties, and solanine hydrochloride has been used as a commercial pesticide, but never on a large scale. Solanine has sedative and anticonvulsant properties, has been used as a treatment for asthma, and as an anticongestant.
Structural name:
solanid-5-en-3-yl 6-deoxy-β -L-mannopyranosyl-(1->2)-[ β-D-glucopyranosyl-(1->3)]- β-D-galactopyranoside.
Molecular formula: C45H73NO15
Molar weight: 868.06
Melting point: 271 - 273 °C
CAS registry Number: 20562-02-1