Demissidine CAS 474-08-8

Demissidine is found in significant concentration in unripe potato skins (as a glycoalkaloid). The alkaloid is reported to inhibit cholinesterase, disrupt cell membranes, and induce teratogenicity most probably indicating activity through inhibition of DNA topoisomerase II.

Demissidine has been shown to have DNA-modifying activities. In addition, when tested for antibacterial attributes, Demissidine showed activity against Staphylococcus aureus.

Structural name: (22S,25S)-5-α-Solanidan-3-β-ol

Molecular formula: C27H45NO

Molecular weight: 399.65

Cas Registry number: 474-08-8